Development and evaluation of multiplex and high-throughput SNP analysis for the ABCA1 gene [Elektronische Ressource] / vorgelegt von Mario C. O. Probst

Development and Evaluation of Multiplex and High-throughput SNP Analysis for the ABCA1 gene Dissertation zur Erlangung des Doktorgrades der Naturwissenschaften (Dr. rer. nat.) an der Fakultät für Chemie und Pharmazie der Universität Regensburg vorgelegt von Mario C.O. Probst Regensburg im März 2004 Development and Evaluation of Multiplex and High-throughput SNP Analysis for the ABCA1 gene Doctoral Thesis by Mario C.O. Probst This work was performed at the Institute of Clinical Chemistry and Laboratory Medicine at the University of Regensburg between September 1999 and December 2003 under the supervision of Prof. Gerd Schmitz. Date of colloquium: March 29, 2004 Board of examiners: Chairperson: Prof. Hartmut Krienke First expert: Prof. Otto S. Wolfbeis Second expert: Prof. Gerd Schmitz Third expert: Prof. Manfred Liefländer I “The aim of science is not to open the door to infinite wisdom, but to set a limit to infinite error”. Berthold Brecht, “The Life of Galileo“ II Acknowledgements Above all, I would like to thank Prof. Gerd Schmitz for providing the fascinating technological facilities at his institute. He also gave me the opportunity and support to visit various conferences and workshops and to participate in several interesting research projects.